One capsule in the evening, with or without food... Dongwha Pharmaceutical launches 'Pravapen Capsules'

Dongwha Pharmaceutical said on October 22 that it had launched Pravapen Capsules, a combination drug for dyslipidemia that manages LDL cholesterol, triglycerides and HDL cholesterol together.

Product image of Dongwha Pharmaceutical's combination drug for dyslipidemia, Pravapen Capsules. Dongwha Pharmaceutical

Pravapen Capsules combine 40 mg of pravastatin sodium and 110 mg of fenofibric acid. The drug is used for patients with mixed dyslipidemia who are at high risk of coronary heart disease (CHD) and whose LDL cholesterol is controlled with pravastatin 40 mg alone, but who have high triglyceride levels and low HDL cholesterol.

Dyslipidemia refers to a condition in which blood levels of LDL cholesterol or triglycerides are high, or HDL cholesterol is low. Some patients continue to have high triglyceride levels and low HDL cholesterol even after their LDL cholesterol is controlled, so treatment should take both lipid levels and cardiovascular risk factors into account.

Pravapen Capsules use two ingredients with different mechanisms of action to manage key lipid levels together. Pravastatin lowers LDL cholesterol by inhibiting cholesterol synthesis in the liver, while fenofibric acid reduces triglycerides and improves HDL cholesterol. Fenofibric acid is the active form of fenofibrate and acts directly in the body without requiring a separate activation process.

The capsules are also designed to make dosing more convenient. Some existing fenofibrate products must be taken with or after food because food affects drug absorption. Pravapen Capsules can be taken once a day in the evening, with or without food. The capsules are also smaller than those of existing combination drugs.

Dongwha Pharmaceutical plans to hold a symposium to mark the launch of Pravapen Capsules on October 31 at the Sofitel Ambassador Seoul Hotel in Songpa-gu, Seoul. The company will share treatment strategies for mixed dyslipidemia and ways to apply them in clinical practice.

This content was produced with the assistance of AI translation services.