Tick-Triggered "Alpha-Gal Syndrome" on the Rise
Hard to Identify the Cause, Unlike Typical Allergies

A woman in the United States was recently diagnosed with alpha-gal syndrome, a rare allergic condition triggered by tick bites, after suffering such severe abdominal pain after eating a hamburger that it woke her from sleep.


"My Stomach Was in Knots All Night After Eating a Hamburger"... Woman's Surprise Diagnosis After Tests Came Back Normal View original image

According to People magazine and CBS, Angela Lundy, who lives in Pennsylvania, first noticed something was wrong after eating sausage in June. A week later, after sharing a hamburger with her husband, she suffered severe abdominal pain for three hours. Angela initially suspected a digestive condition, such as gallstones, but her test results were normal.


As she continued to suffer without knowing the cause, an acquaintance told her, "A tick bite can cause a meat allergy." Angela then remembered being bitten by a tick in early June and experiencing severe itching. A blood test confirmed that she had alpha-gal syndrome.


Alpha-gal syndrome is a condition in which a person has an allergic reaction to the meat of mammals such as cows, pigs, and sheep after being bitten by certain ticks. It is caused by a sugar molecule called galactose-alpha-1,3-galactose (alpha-gal). Alpha-gal is found in most mammals, but is not naturally produced in the human body.

If you experience severe abdominal pain after eating a hamburger, you should suspect alpha-gal syndrome, a rare allergic condition. Pixabay

If you experience severe abdominal pain after eating a hamburger, you should suspect alpha-gal syndrome, a rare allergic condition. Pixabay

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The problem is that the saliva of some ticks contains alpha-gal. When alpha-gal enters the body through a tick bite, the immune system recognizes it as a threat. Later, when a person eats beef or pork, the immune system reacts, causing allergic symptoms such as hives, vomiting, and abdominal pain.


Alpha-gal syndrome is potentially fatal because, unlike common food allergies, its symptoms appear with a delay. Most allergic reactions occur soon after eating the food that triggers them, but alpha-gal syndrome symptoms usually appear about 2 to 6 hours after eating meat. Someone may eat meat for dinner, go to bed feeling fine, and wake in the middle of the night in severe pain. Because of this delay, patients may have difficulty realizing that meat is the cause.


Symptoms range from mild indigestion to severe abdominal pain, diarrhea, and widespread hives. In severe cases, anaphylaxis, a sudden, widespread allergic reaction, can cause difficulty breathing and become life-threatening. It is even harder to identify the condition because the same symptoms do not necessarily occur every time a person eats meat.


People with this condition may also have allergic reactions to milk, dairy products, foods containing gelatin, and medicines derived from mammals, so caution is needed.


The U.S. Centers for Disease Control and Prevention (CDC) estimates that up to 450,000 people in the United States may be affected by alpha-gal syndrome. There is currently no preventive vaccine or treatment that addresses the underlying cause, so the only way to manage the condition is to strictly avoid the foods that trigger it and prevent further tick bites. According to the CDC, the syndrome is known to occur mainly after bites from the Lone Star tick.



If you have been bitten by a tick after spending time outdoors and repeatedly experience unexplained abdominal pain or hives several hours after eating meat, you should see an allergist for an accurate diagnosis.


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