Oh Yookyung, Minister of Food and Drug Safety: "A rare but possible side effect"

A suspected case of vision impairment following treatment with a glucagon-like peptide-1 (GLP-1) drug for obesity or diabetes has also been reported in South Korea.


Oh Yukyung, Minister of Food and Drug Safety, answers lawmakers' questions during a parliamentary audit of the ministry and other agencies at the National Assembly on Oct. 13, 2026. Photo by Yoon Dongju

Oh Yukyung, Minister of Food and Drug Safety, answers lawmakers' questions during a parliamentary audit of the ministry and other agencies at the National Assembly on Oct. 13, 2026. Photo by Yoon Dongju

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Minister of Food and Drug Safety Oh Yu-kyung said at a parliamentary audit held on the 13th by the National Assembly Health and Welfare Committee that one case had been reported in December 2024. She was responding to a question from Baek Seon-hee of the Rebuilding Korea Party, who asked whether there had been a suspected case of vision impairment caused by NAION after the use of a GLP-1 obesity drug.


NAION, known as a "stroke of the eye," is the second-leading cause of blindness resulting from damage to the optic nerve, after glaucoma. It is caused by a lack of blood supply to the optic nerve and can lead to permanent blindness.


In the United States, patients have filed a series of lawsuits against pharmaceutical companies, claiming they suffered vision loss after using GLP-1 drugs for obesity or diabetes.

Although a causal link between GLP-1 drugs and NAION has not been clearly established, the European Medicines Agency (EMA) designated NAION in June 2025 as a "very rare side effect" of semaglutide, the active ingredient in these drugs.



In this regard, Minister Oh said, "The Ministry of Food and Drug Safety also recognized it as a side effect on October 7," adding, "It is now listed as a 'rare but possible side effect.'"


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