Nuon has received approval from the Ministry of Food and Drug Safety for a new functional claim for its individually recognized ingredient, “Terminalia Chebula Extract (AyuFlex®).”


Nuon Receives MFDS Functional Approval for Terminalia Chebula Extract View original image

According to Nuon on September 4, human application trials conducted over eight weeks demonstrated a clear reduction in swelling. Significant reductions in circumference were observed in key measurement areas related to leg discomfort compared to the control group. In addition, subjective symptoms such as swelling and heaviness also improved relative to the control group.


The company explained that this recognition is significant because it targets an area in the functional health food market that previously lacked clear solutions. The product can address practical needs for people who spend long hours sitting or standing at work, as well as for modern consumers who frequently travel long distances.


Terminalia Chebula Extract is a dual-functional ingredient that has previously been recognized for its potential to support joint and cartilage health. Mechanistic studies have confirmed that the ingredient simultaneously modulates inflammatory responses and vascular functions. At the cellular level, it has demonstrated antioxidant effects, reduced inflammatory cytokines, and protected blood vessels by restoring endothelial cell barriers.


Studies in animal models confirmed that the extract reduces vascular permeability and suppresses inflammatory edema. It is designed for a daily intake of 500 mg, and no significant safety issues were reported during safety assessments.



A Nuon representative stated, "The individual recognition of Terminalia Chebula Extract marks the first official acknowledgment in Korea of its potential to reduce leg swelling. Starting with the launch of a functional health food for leg swelling improvement, which utilizes the newly approved ingredient within this year, we plan to expand our product line to include items such as calf patches and target the global market as well."


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